Publications & Media

Publications

Green, A. T.; Moniruzzaman, M.; Cooper, C. J.; Walker, J. K.; Smith, J. C.; Parks, J. M.; Zgurskaya, H. I. Discovery of multidrug efflux pump inhibitors with a novel chemical scaffold. Biochimica et Biophysica Acta, General Subjects. 1864(6):129546, 2020.

Mansbach, R. A.; Leus, I. V.; Mehla, J.; Lopez, C. A.; Walker, J. K.; Rybenkov, V. V.; Hengartner, N. W.; Zqurskaya, H. I.; Gnanakaran, S. Development of a fragment-based machine learning algorithm for designing hybrid drugs optimized for permeating gram-negative bacteria. Quantitative Biology. 1-19. 2019.

Zhao, H.; Petrushenko, Z.; Walker, J.; Baudry, J.; Zgurskaya, H.; Rybenkov, V. Small molecule condensin inhibitors. ACS Infect Dis. 4(12):1737, Oct. 2018. PMID:30346684

Cooper, S.J.; Krishnamoorthy, G.; Wolloscheck, D.; Walker, J.K.; Rybenkov, V.V.; Parks, J. M.; Zgurskaya, H.I. Molecular Properties That Define the Activities of Antibiotics in Escherichia coli and Pseudomonas aeruginosa. ACS Infect Dis. 4(8):1223, May 2018. PMID:29756762

Woehl, Jordan L.; Raymar, Karsa X.; Katz, Benjamin B.; Walker, John K.; Geisbrecht, Brian V. The structural basis for inhibition of the classical and lectin complement pathways by S. Aureus extracellular adherence protein. Protein Sci. 26(8):1595. Aug, 2017. PMID 28512867

Haynes, K.M.; Abdali, N.; Jhawar, V.; Zgurskaya, H.I.; Parks, J.M.; Green, A.; Baudry, J.; Rybenkov, V.V.; Smith, J.C.; Walker, J.K.* Identification and Structure-Activity Relationships of Novel Compounds that Potentiate the Activities of Antibiotics in Escherichia col. J Med Chem. 60(14):6205. Jul, 2017. PMID:28650638

Abdali, N.; Parks, J. M.; Haynes, K. M.; Chaney, J. L.; Green, A. T.; Wolloscheck, D.; Walker, J. K.; Rybenkov, V. V.; Baudry, j.; Smith, J. C.; Zgurskaya, H. I. Reviving antibiotics: efflux inhibitors with a new mechanism of action. ACS Infect Dis. 3(1):89. Jan, 2017. PMID 2829852301/17

Garcia, B.; Skaff, A.; Wyckoff, G.; Walker, J.K.; Hanning, A.; Chatterjee, A.; Giesbrecht, B.V. Identification of C3b-Binding Small-Molecule Complement Inhibitors Using Cheminformatics. J Immunol. 198(9): 3705. 2017. PMID 28298523

Wang, Y.; Billon, C.; Walker, J.K.; Burris, T.P. Therapeutic Effect of a Synthetic RORa/g Agonist in an Animal Model of Autism. ACS Chem Neurosci. 7(2):143, Feb, 2016. PMID:26625251